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Pressetext: Kein ‚Blindflug' bei unregelmäßiger Monatsblutung
Gynäkologenduo warnt vor veralteter Curettage.

"Die Regelmäßigkeit der Regelblutung - individuell unterschiedlich aber durchschnittlich alle 28 Tage - signalisiert Frauen, dass sie sich nicht sorgen müssen, dass also ‚alles in Ordnung' ist", sagen Prof. Paul Speiser und Prof. Fritz Nagele, Gynäkologen am AKH. "Aber für einige ist die Monatsblutung eine Tortur: mit Schmerzen einhergehend, unregelmäßig, stark verlängert. Blutungsstörungen sind der häufigste Grund für den Gang zum Frauenarzt: Jede dritte Frau geht deswegen zum Gynäkologen - nach dem Klimakterium sind Blutungsstörungen sogar der Grund für 70 % aller Besuche beim Gynäkologen."
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Message Board www.endofem.at
Das Message Board von www.endofem.at ist wieder online.

 

Pressetext: Frauen fühlen eine starke Beziehung zu ihren inneren Organen
Gebärmutter und Eierstöcke haben identitätstragenden Aufgaben

"Viel zu oft wird gleich das ganze Organ herausgeschnitten, obwohl nur ein Teil davon krankhaft verändert ist", kritisieren die beiden Frauenärzte am Wiener AKH Prof. Fritz Nagele und Prof. Paul Speiser den allgemeinen Gynäkologie-Betrieb. Und weiter: "Den Schaden haben die Patientinnen: von Beeinträchtigungen ihres Wohlbefinden bis hin zu Orgasmusproblemen und Identitätskrisen. Denn Gebärmutter und Eierstöcke sind frauenspezifische und daher identitätstragende Organe, zu denen Frauen eine sehr sensible Beziehung entwickeln.
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Zum Thema Myomembolisation
Offizielle Stellungnahme der Arbeitsgemeinschaft für Gynäkolgische Endoskopie der Österreichischen Gesellschaft für Gynäkologie und Geburtshilfe, Protokoll Jänner 2001

"In den letzten Monaten wurde vor allem in den Medien eine neuartige Behandlungsform von Myomen unkritisch propagiert. Die Technik der selektiven Myomembolisation stellt eine neue Methode dar, die noch nicht durch ausreichende Langzeitergebnisse untermauert ist. Die Komplikationsraten, das Follow-up, die richtige Patientenselektion sowie die notwendige (bis zu 48 Stunden) intensive Schmerztherapie postoperativ wurden von den Protagonisten dieser Therapie nicht ausreichend erwähnt. Ebenso die Tatsache, dass Erfahrungen bei Patientinnen mit noch vorhandenem Kinderwunsch fehlen, wurde nicht genügend Beachtung geschenkt. Wir sehen uns daher als Arbeitsgemeinschaft verpflichtet, darauf zu reagieren. Auf Grund der wissenschaftlichen Datenlage soll eine Myomembolisation derzeit nur unter kontrollierten Studienbedingungen durchgeführt werden. Die Patientinnen müssen über die zu erwartenden Nebenwirkungen und Komplikationsraten dieser Behandlung ausführlich aufgeklärt werden. Als Alternativen sind unbedingt die bewährten Alternativen wie operative konservative Myomenukleation, die Hysterektomie oder Zuwarten anzubieten. Dies ist auch in der Aufklärung zu erwähnen. Der Einsatz der Myomembolisation außerhalb von klinischen Studien kann erst nach Vorliegen von Langzeitergebnissen dieser Methode und Definition des geeigneten Patientenkollektivs erfolgen."

 

Vortragsreihe Prof. Nagele  
Myome - die häufigsten gutartigen Tumore der Frau
Datum: Donnerstag 1.März 2001, 19:00 Uhr
Ort: Volkshochschule Alsergrund, Galileigasse 8, 1090 Wien
 
Endometriose - die rätselhafte Erkrankung
Datum: Donnerstag 8.März 2001, 19:00 Uhr
Ort: Volkshochschule Alsergrund, Galileigasse 8, 1090 Wien
 
Wandel in Diagnostik und Therapie bei Zysten, Myomen und Gewächsen
im Bereich der Eierstöcke und Bauchhöhle. Sind Bauchoperationen vermeidbar?
Datum: Montag 21.Mai 2001, 16:30 Uhr
Ort: Planetarium der Stadt Wien, Oswald-Thomas-Platz 1, 1020 Wien
 

 

Interstitial Cystitis Is Poorly Understood Syndrome  

WESTPORT, CT (Reuters Health) Jan 05 - The large number of diverse treatments for interstitial cystitis (IC) reflect a lack of understanding about the management of this disease, as well as the absence of effective treatments, according to a report in the December issue of Urology.

Dr. Kathleen Joy Propert, of the University of Pennsylvania School of Medicine, Philadelphia, and
colleagues with the Interstitial Cystitis Data Base (ICDB) study group sought to assess the frequency and
types of treatments reported at baseline by 581 women who enrolled in the ICDB cohort study between
1993 and 1997.

"The number and types of treatments were evaluated with respect to baseline factors such as prior
diagnosis of IC and symptom severity," the researchers explain.

At baseline, 105 (18%) women were not receiving therapy, according to the investigators. One hundred
ninety-five (34%) women were receiving single-mode therapy, while 119 (21%) were receiving a
combination of two treatments and 162 (28%) were receiving three or more treatments. "A total of 183
different types of therapies were recorded," they say.

The five most commonly used therapies for IC symptoms included cystoscopy and hydrodistention (32.9%),
amitriptyline (16.9%), phenazopyridine (14.3%), special diet (9.3%), and intravesical heparin (9.1%).
"Because most patients entered the ICDB before the approval of oral pentosan polysulfate sodium (PPS),
only 6% of women reported oral PPS use at baseline," the team notes.

The researchers observed significant associations between the number and types of therapies and the
clinical center, a prior diagnosis of IC, and severity of symptoms.

Dr. Propert's team concludes that "evidence-based outcomes research and randomized clinical trials are
needed to define optimal therapeutic regimens until such time as the underlying etiology and pathophysiology
of IC is better understood and rational etiologically based therapy can be initiated."

Urology 2000;56:940-945.

 

Hypertension and Pelvic Inflammatory Disease
Increase The Risk of Uterine Leiomyoma
 

WESTPORT, CT (Reuters Health) Jan 05 - Three recent studies have documented that hormone-related
characteristics are not the only risk factors for uterine leiomyoma.

What little information exists about risk factors for fibroids is limited by numerous methodologic deficiencies,
Dr. Stephen M. Schwartz notes in an editorial accompanying the three reports in the January 1st issue of the
American Journal of Epidemiology. The new studies are particularly noteworthy, he says, because they
attempt to address these shortfalls.

In the first of two studies, Dr. Eduardo Faerstein, of Universidade do Estado do Rio de Janeiro, in Brazil, and
US colleagues looked for potential risk factors in 318 premenopausal women with surgically or sonographically
confirmed fibroids and 394 controls from the population of women living in Baltimore, Maryland. Cases
included women with symptomatic fibroids, as well as some with asymptomatic disease first suspected during a
pelvic examination.

The results confirmed prior reports of associations between uterine fibroids and hormonal risk factors. For
instance, both early menarche and high body mass index increased the risk of having a fibroid by nearly
2.5-fold, while the use of oral contraceptives (odds ratio 0.2) and a history of long-term smoking (odds ratio
0.6) lowered the risk.

The investigators also found that African-American women were more than nine times as likely as white
women to develop fibroids. While this relationship has been previously reported, the association was "much
stronger" than in prior studies, including the Nurses' Health Study, and "was strengthened after we controlled
for markers of health behavior," they explain.

In their second study, Dr. Faerstein's group "push the field even further...with the first systematic investigation
of etiologic relations that extend beyond hypotheses focused on steroid hormones," Dr. Schwartz says in his
editorial. Dr. Schwartz is affiliated with the Fred Hutchinson Cancer Research Center, Seattle, Washington,

For instance, the researchers demonstrated significant increases in the risk of fibroids in women with
hypertension (particularly of more than 5 years' duration), a history of pelvic inflammatory disease, past
chlamydial infection or a history of intrauterine device use associated with infectious complications. They also
noted a doubling of risk in women who reported daily perineal talc use compared with those who reported no
use of talc in this region.

Dr. Schwartz told Reuters Health that a particularly important result of the two studies is the suggestion that
the "association between a history of infertility and subsequent risk of being diagnosed with fibroids, which is
commonly mentioned in the clinical literature but not well studied epidemiologically, may well be due to the
tendency for some fibroids (those that project into the uterine cavity) to cause problems with childbearing."

"I think this has been suspected for some time but not previously demonstrated in a research study," he
explained.

In the third report, Dr. Jean Wactawski-Wende, from the University of Buffalo in New York, and associates
note that while most prior research on fibroids has been conducted in symptomatic women, nearly half of all
fibroids are never symptomatic. They addressed this inconsistency in a study of risk factors for fibroids in
women undergoing tubal sterilization.

Of 3,171 subjects, a total of 317 had uterine fibroids, including 196 whose fibroids were asymptomatic and
identified at the time of surgery. The investigators addressed a second methodologic flaw in prior research by,
for the first time, examining the roles of various risk factors separately in white and African-American women.

"With the exception of advancing age, our data suggest that risk factors may not be consistent for all racial
subgroups," Dr. Wactawski-Wende told Reuters Health. Advancing age (40 to 44 years) was the only
significant risk factor for fibroids in African-American women, increasing the risk by 27.5-fold.

In contrast, several significant risk factors emerged in white women, including advancing age, an interval of
more than 5 years since last delivery, a history of smoking at least one pack of cigarettes per day, a menstrual
cycle longer than 30 days and menstrual bleeding for 6 days or longer.

"A key question that still needs to be answered," Dr. Schwartz said in the interview with Reuters Health, "is
what distinguishes the women with fibroids that go on to cause symptoms (and thus, surgical procedures like
hysterectomy) from those women with fibroids that do not go on to cause symptoms, and what distinguishes
this latter group from women who don't develop fibroids at all."

Am J Epidemiol 2001;153:1-30.

 

Einladung der "University New South Wales"  

Prof. Speiser hielt auf Einladung der "University NSW" am 29. Dezember einen Vortag zum Thema "Expression of CD44 Variant Proteins in Vulvar Carcinoma of Patients in Western Australia".

 

Einladung der "University of Queensland"  

Prof. Speiser war vom 4. bis 10. Jänner am "Centre for Gynaecological Cancer" des "Royal Women's Hospital" in Brisbane zum gemeinsamen Operieren eingeladen. Sinn der Einladung war der Austausch von chirurgischen Techniken.

 

Women Are Unaware of Alternatives to Hysterectomy for Menorrhagia  
December 4, 2000 MedscapeWire  

According to a recent survey by the Society for Women's Health Research (SWHR), two thirds of American women are unaware of alternatives to hysterectomy for treating excessive menstrual bleeding. Presently 1 in 5 women is affected by excessive menstrual bleeding, or menorrhagia, and experience unmanageable bleeding resulting in a constant need to change sanitary products.

Due to the frequency with which hysterectomy is performed for excessive menstrual bleeding, SWHR examined physicians' and patients' awareness of hysterectomy as well as alternative options. Survey results show that doctors recommend hysterectomies to about 1 in 4 women. Of those, 82% accept their doctor's recommendation. The survey also revealed that more than one third of women who had a hysterectomy did not discuss potential alternatives with their doctor. However, the majority of physicians (75%) supported their patient's efforts to research alternatives.

"Women need to know that it is appropriate to question procedures and feel comfortable discussing options with their physicians," said Phyllis Greenberger, PhD, executive director of SWHR. "Open dialogue can help women make informed choices when it comes to excessive menstrual bleeding or any condition."

Hysterectomy is the second most common surgery performed on women, and may be recommended for benign uterine conditions, such as excessive menstrual bleeding or fibroids. Twenty percent of the 600,000 hysterectomies performed annually in the United States are for excessive menstrual bleeding. The procedure is also used to treat cancer and pelvic support problems.

"Women with excessive menstrual bleeding may frequently find that they have to go to great lengths to prevent potential embarrassments," said Gerson Weiss, MD, professor and chairman of the Department of Obstetrics and Gynecology at New Jersey Medical School. "It's important that a woman talk with her physician about her diagnosis, as well as alternative, and perhaps less invasive options for dealing with excessive menstrual bleeding."

 

Existence of Post-Tubal-Ligation Syndrome Refuted  
N Engl J Med 2000;343:1681-1687,1724-1726.  

WESTPORT, CT (Reuters Health) Dec 06 - Tubal sterilization does not increase the risk of menstrual abnormalities, report investigators with the US Collaborative Review of Sterilization Working Group. This finding refutes accounts of the existence of a post-tubal-ligation syndrome that includes heavy bleeding and intermenstrual bleeding.

Dr. Herbert B. Peterson, from the US Centers for Disease Control and Prevention in Atlanta, and colleagues compared outcomes over 5 years of 9514 women who underwent tubal sterilization and 573 women whose partners underwent vasectomy. They report their findings in the New England Journal of Medicine for December 7.

"We've had a half century of debate about whether or not the so-called post-tubal-ligation syndrome exists," Dr. Peterson told Reuters Health. "The belief that menstrual problems do occur is so widespread it's been given a name."

"The proportion of women with persistent menstrual changes varied according to baseline menstrual status in both study groups," he and his associates write in the journal.

"We can take a biologic explanation out of the equation," Dr. Peterson said. "That's very reassuring, that the major safety question that has been raised has been resolved. This really closes the door on that question."

Dr. Peterson and his colleagues attribute reports of a post-tubal ligation syndrome to the fact that "tubal sterilization and menstrual abnormalities are common and are therefore likely to occur coincidentally." Also at issue are menstrual abnormalities that accompany the cessation of oral contraceptives upon sterilization.

"It's important that women who are contemplating sterilization, if they are worried about it, can be reassured," Dr. Peterson said. "Also, women that have been sterilized and have menstrual abnormalities, and their clinicians, can look at this issue without the sterilization procedure per se being part of the equation."

In an accompanying editorial, Dr. Carolyn Westhoff, of Columbia University in New York, notes that "no other study of these issues offers prospective data acquired in repeated interviews from such a large cohort over such a long period."

Dr. Westhoff points out that women with less troublesome periods at baseline tended to have worsening periods over time, while those with more problematic periods tended to improve, regardless of which group they were in. She also notes that women who had average menstrual flow at baseline were much more likely to experience heavier flow in the next 5 years.

"This increase in flow...not attributable to any intervention," Dr. Westhoff writes, "is a predictable change that women may appreciate being forewarned about."

 

Einladung der Karl Universität in Pilsen  

Auf persönliche Einladung des Leiters der Abteilung für Gynäkologie und Geburtshilfe der Karl Universität in Pilsen, Dozent Rokita, hat Prof. Speiser am 22. und 23. November 2000 folgende Operationen im Rahmen von Lehroperationen durchgeführt: Debulkingoperation bei einer Patientin mit Ovarialkarzinom, radikale Hysterektomie mit pelviner und para-aortaler Lymphknotendissektion bei einer Patientin mit Zervixkarzinom, laparoskopisch assistierte vaginale Hysterektomie bei einer Patientin mit therapieresistenten Blutungsstörungen und eine totale laparoskopische Hysterektomie bei einer Patientin mit Myomen. Der Aufenthalt war ein großer Erfolg und der Beginn einer intensiven Zusammenarbeit.
Weiters hielt Prof Speiser Vorträge zu den Themen laparoskopische Dissektion der Beckenlymphknoten und Management des klinisch frühen Endometriumkarzinom.

 

Pelvic Congestion -  
Eine neue Technik kommt in Österreich zum ersten Mal zur Anwendung

Am 28. November hat Prof. Speiser, vermutlich zum ersten Mal in Österreich, eine Untersuchung bei einer Patientin mit chronischen Unterbauchschmerzen und Verdacht auf Beckenvenenstau durchgeführt. Zur Anwendung kam ein Instrument der Firma "Rocket Medicals" mit dessen Hilfe eine Kontrastmitteldarstellung der Beckenvenen durchgeführt werden kann. Die gewonnen Röntgenbilder waren von hervorragender Qualität und lieferten die gewünschte Information.

 

Vortrag Prof. Nagele  

Zum Thema "IVM bei Patientinnen mit PCO-Syndrom", "Chronic Pelvic Pain"
Ort: Gesellschaft der Ärzte, Frankgasse 8, 1090 Wien
Zeit: Samstag,11.November 2000, 09:00-11:00 Uhr